Page 205 - Livre électronique des RFTP 2024

FREQUENCY AND CHARACTERISTICS OF

DYSANAPSIS IN A TUNISIAN POPULATION : A
RETROSPECTIVE STUDY ABOUT 7199 PATIENTS

CHAIMA BRIKI1, BALSAM BARKOUS1,2, WIEM BEN HMID1, SONIA ROUATBI1,2, HELMI
BEN SAAD1,2

1 DEPARTMENT OF PHYSIOLOGY AND FUNCTIONAL EXPLORATIONS, UNIVERSITY HOSPITAL OF
FARHAT HACHED, SOUSSE, TUNISIA 2 RESEARCH LABORATORY HEART FAILURE, LR12SP09,
UNIVERSITY HOSPITAL OF FARHAT HACHED, SOUSSE, TUNISIA

INTRODUCTION.Dysanapsisis is characterized by a spirometric pattern featuring a
low FEV1/FVC ratio alongside a normal FEV1, which is observed during maximal
effort. In healthy individuals, this pattern may stem from unequal growth of airways
and lung parenchyma or serve as an indicator of predisposition to obstructive lung
diseases.
OBJECTIVES. To ascertain the frequency of dysanapsis in a Tunisian population
and delineate the anthropometric and baseline spirometric profiles of individuals
exhibiting dysanapsis.

METHODS. A retrospective analysis was conducted on spirometric records from
patients referred for pulmonary function assessment. Age, height, weight, body
mass index (BMI), were determined, and spirometric data (eg; FEV1, FVC, and
FEV1/FVC) were collected, adhering to 2019 ERS-ATS technical standards.

RESULTS. Among 7199 included patients, dysanapsiswaswas identified in 179
individuals (2.5%). The mean±SDof age, height, and BMI of these 179 patients were
37.7±21.6 years, 161±19 cm, and 23.8±5.3 kg/m2, respectively, and10.1% and 29.1% of
patients were classified as obese and overweight, respectively. The mean±SDof
FEV1 (L, %, z-score),FVC (L, %, z-score) and FEV1/FVC (absolute, z-score),were
2.78±0.98 L, 90±13%, and -0.74±0.98, 4.12±1.45 L,109±17%and 0.68±1.19, and
0.68±0.06and -2.00±0.34, respectively.

CONCLUSION. The frequency of dysanapsis in the studied population stands at
2.5%. Patients exhibiting dysanaptic patterns tend to be relatively younger with
normal BMI and FVC values.

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