Page 232 - Livre électronique des RFTP 2024

ANXIETY, DEPRESSION, AND SLEEP DISORDERS IN

POST-COVID-19 PATIENTS ONE YEAR AFTER ICU
DISCHARGE

MARIEM ABDESSLEM1,2 , MARWA ZGUIDI 3, NADIA BEN LAZREG1,2, FATMA GUEZGUEZ,
1,2, SONIA ROUATBI,1,2

1UNIVERSITE DE SOUSSE, HOPITAL FARHAT HACHED, SERVICE DE PHYSIOLOGIE ET
EXPLORATIONS FONCTIONNELLES, SOUSSE,TUNISIE. 2UNIVERSITE DE SOUSSE, HOPITAL
FARHAT HACHED, LABORATOIRE DE RECHERCHE « L’INSUFFISANCE CARDIAQUE » (LR12SP09),
SOUSSE, TUNISIE. 3UNIVERSITE DE SOUSSE, HOPITAL FARHAT HACHED, SERVICE DE
REANIMATION MEDICALE, SOUSSE, TUNISIE.

INTRODUCTION COVID-19 is a serious disease that can significantly affect the
mental health problems such as depression, anxiety and insomnia. It may lead to a
negative impact on physical and social domains of post ICU covid-19 patients
health in the long term.

AIM: to determine the frequency and risk factors of anxiety, depression and poor
sleep quality in post severe COVID-19 patients one year after ICU discharge and to
evaluate the correlations between these outcomes.

METHODS: It was a prospective observational study including patients hospitalized
for severe forms of COVID-19 between March 2020 and December 2021 in a
medical ICU for at least 48 hours and who discharged alive. One year post ICU
discharge, Depression, and anxiety were assessed using the Hospital Anxiety and
Depression Scale (HADS). A cut off HADS-A≥11 and HADS-D≥ 11 confirm the
diagnosis of anxiety and depression respectively. The sleep quality was assessed
by Pittsburgh sleep quality questionnaire (PQSI), a score≥5 indicated a poor sleep
quality
RESULTS: 732 patients were admitted to the ICU, 465(63.5%) had a confirmed
COVID-19 infection. Of these patients, 175(37.6%) died during ICU admission.
Among the 290 patients discharged alive, 14(4.8%) died, 104(35.8%) were not
reachable or refused to partcipate.36 patients met the inclusion criteria.

Patients' characteristics were: 26(72%) patients were male; Median age, 56 [49-65]
years; Median SAPSII on admission, 27[26-30]; Median Charlson comorbidity
index(CCI), 1[0-2]; Median length-of-ICU-stay (LoS), 8[5-12] days; Invasive
mechanical ventilation (IMV), 8(22.2%) patients.

One year after discharge, Mean anxiety score, 7±3; mean depression score, 8±3,
anxiety(HADS-A>11), 11(31.4.%); depression (HADS-D≥11), 12(34.3%). Mean global
PSQI score, 6 ±3, Poor sleep quality (global PSQI score ≥ 5), 18(50%) patients;
11(30.5%)patients reported sleep difficulties, with mean scores ≥ 2 for sleep
disturbances, and sleep latency.

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